Cover design for the article “Cell plasticity in Caenorhabditis elegans: From induced to natural cell reprogramming” published in the journal Genesis. Transdifferentiation is the direct cell reprogramming of a differentiated cell into another specialized cell type. In the worm Caenorhabditis elegans, an epithelial-to-neuronal transdifferentiation (the “Reset button”) occurs naturally in vivo.

The illustration depicting cell fate reprogramming has been chosen by the journal Genesis for its cover on the January issue in 2012.

See the journal website: